Application of compressed gas in pharmacy
Natural dry air (compressed air) is a colorless, odorless and tasteless mixture of gases. The dry air product is made up of 21% high-purity oxygen +79% high-purity nitrogen. Dry air is widely used as a pure combustion gas in gas chromatograph, mass connection and atomic absorption apparatus. Generally, it is packaged by 40L high-pressure cylinder with a pressure of 13.5MPa. The actual volume is about 5.4m3, that is, 5,400 standard liters
Compressed air is a major power source in drug production. According to GMP, "the compressed air in direct contact with the medicine shall be purified to meet the production requirements". However, in the actual production, there are many difficulties in compressed air purification, and the traditional compressed air purification mode is too complicated and the operation cost is very high. Therefore, the new compressed air purification equipment with low energy consumption, strong applicability and simple use has become the research and development hotspot. International trade co., LTD., nanjing potential of engineering and technical personnel through in-depth pharmaceutical companies to carry out joint research, its has gained international invention patent of 3 in1 series multi-function compressed air filter for technical improvements, making the equipment successfully shandong pharmaceutical glass co., LTD., China pharmaceutical university and other companies for laboratory applications and production. Recent usage reports from these companies show significant improvements in energy consumption, ease of use and other aspects of the filter.
Compressed air has become the second largest energy source in modern industry after electricity. The use of compressed air as a source of energy in developed countries is doubling about every five years. In the field of drug production, it runs through fermentation, crystallization, drying, filtration and other processes. In the production of antibiotics and other drugs, the quality of compressed air is required to be very high, not only there is no oil or water in the compressed air, but more importantly, it should be dust-free and sterile. According to scientific statistics, if the original 8 cubic meters of air under normal pressure is compressed to 1 cubic meter, 0.8 mpa of compressed air can be formed, and there will be 320 million ~ 400 million dust particles larger than 0.5 micron in the 1 cubic meter of compressed air. In addition, the atmosphere in the process of being compressed, will be brought into the air compressor lubricating oil and mechanical grinding debris. And the compressed air will have a large number of supersaturated water vapor reduced to water droplets. If the water, dust, oil and dirt in the compressed air cannot be cleaned in time, the gas pipeline will be corroded and blocked, resulting in the failure of the pneumatic parts and wear of the mechanical sealing device, which may cause incalculable losses to the pharmaceutical production enterprises. In addition, when compressed air is used as oxygen carrier or nitrogen is used as gas protection, pollutants and miscellaneous bacteria brought in by oil, water and dust will also cause failure of biochemical culture and pollution of drugs. Therefore, it is not easy for enterprises to obtain oil-free, dust-free and sterile compressed air.